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2026
- A human striatal-midbrain assembloid model of alpha-synuclein propagation
Tran HD, Shin MK, Yeo XY et al. Brain · DOI · PubMed - Differential MicroRNA Expression in Chronic Spontaneous Urticaria in Relation to Treatment Response
Lee Y, Noh JY, Yoon J et al. Allergy Asthma Immunol Res · DOI · PubMed - Distinct Serum MicroRNA Signatures and mRNA Decay Pathway Dysregulation in NSAID-Exacerbated Chronic Urticaria
Ye YM, Noh JY, Kim SH et al. Int J Mol Sci · DOI · PubMed - Engineered flower-like core-double-shell upconversion nanoarchitectures for ultrasensitive activatable FRET imaging of cathepsin B in vitro and in vivo
Abualrejal MMA, Shah M, Lgaz H et al. Talanta · DOI · PubMed - Enhanced multicancer screening assay through whole-genome methylation sequencing-based multimodal cell-free DNA analysis
Jeong S, Go D, Jeon Y et al. Exp Mol Med · DOI · PubMed - Mitochondrial transfer in cancer: mechanisms, immune evasion, and therapeutic opportunities
Ka HI, Woo HG. Genomics Inform · DOI · PubMed
2025
- BIGPN: Biologically informed graph propagational network for plasma proteomic profiling of neurodegenerative biomarkers
Park S, Lee DG, Kim J et al. Artif Intell Med · DOI · PubMed - Cd99l2 regulates excitatory synapse development and restrains immediate-early gene activation
Kang M, Yoon SH, Kang M et al. Cell Rep · DOI · PubMed - Explainable multiplex graph propagational network with multimodal neuroimage integration for dementia subtype diagnosis
Park S, Lee DG, Kim J et al. Neural Netw · DOI · PubMed - KF-NIPT: K-mer and fetal fraction-based estimation of chromosomal anomaly from NIPT data
Kim D, Sohn JY, Cho JH et al. BMC Bioinformatics · DOI · PubMed - ⭐ NeuroFANN: identification of neuropathological subtypes in dementia with plasma proteins by using functionally annotated neural network
Park S, Kim D, Choi JH et al. Brief Bioinform · DOI · PubMed - ⭐ PPIxGPN: plasma proteomic profiling of neurodegenerative biomarkers with protein-protein interaction-based eXplainable graph propagational network
Park S, Lee DG, Kim J et al. Brief Bioinform · DOI · PubMed - Pan-Variant SARS-CoV-2 Vaccines Induce Protective Immunity by Targeting Conserved Epitopes
Shah M, Moon SU, Shin JY et al. Adv Sci (Weinh) · DOI · PubMed - Peptide‑based therapeutics targeting the SLC39A14‑PIWIL2 fusion in hepatocellular carcinoma
Shah M, Moon SU, Choi JH et al. Genomics Inform · DOI · PubMed - Structural insights into antibody-based immunotherapy for hepatocellular carcinoma
Shah M, Hussain M, Woo HG. Genomics Inform · DOI · PubMed - The role of 7-dehydrocholesterol in inducing ER stress and apoptosis of head and neck squamous cell carcinoma
Lee BS, Park YI, Liu H et al. Cancer Lett · DOI · PubMed - Transcriptional Landscape and Biomarker Discovery for Endoplasmic Reticulum Stress in Alzheimer's Disease: An Ex Vivo Study Using Patients-Derived Dermal Fibroblasts
Kim Y, Nam YJ, Yoon S et al. Psychiatry Investig · DOI · PubMed
2024
- A comprehensive report on the FAOPS 2023 teaching workshop and education symposium
Youm JB, Woo HG, Koibuchi N. Adv Physiol Educ · DOI · PubMed - Artificial intelligence-driven drug repositioning uncovers efavirenz as a modulator of α-synuclein propagation: Implications in Parkinson's disease
Kim JB, Kim SJ, So M et al. Biomed Pharmacother · DOI · PubMed - ⭐ Identification of molecular subtypes of dementia by using blood-proteins interaction-aware graph propagational network
Park S, Hong CH, Son SJ et al. Brief Bioinform · DOI · PubMed - Immune checkpoint inhibitor monotherapy is sufficient to promote microenvironmental normalization via the type I interferon pathway in PD-L1-expressing head and neck cancer
Jang JY, Lee BS, Huang M et al. Mol Oncol · DOI · PubMed - Integration of National Health Insurance claims data and animal models reveals fexofenadine as a promising repurposed drug for Parkinson's disease
Kim JB, Kim Y, Kim SJ et al. J Neuroinflammation · DOI · PubMed - ⭐ Integrative transcriptomic and genomic analyses unveil the IFI16 variants and expression as MASLD progression markers
Kim D, Shah M, Kim JH et al. Hepatology · DOI · PubMed - Leveraging deep transfer learning and explainable AI for accurate COVID-19 diagnosis: Insights from a multi-national chest CT scan study
Pham NT, Ko J, Shah M et al. Comput Biol Med · DOI · PubMed - Long Non-coding RNA TPRG1-AS1 Interacts With CLTC in Liver Cancer Cells
Moon SU, Shah M, Thao TT, Woo HG. Anticancer Res · DOI · PubMed - Optimization of vision transformer-based detection of lung diseases from chest X-ray images
Ko J, Park S, Woo HG. BMC Med Inform Decis Mak · DOI · PubMed - Plasma protein-based identification of neuroimage-driven subtypes in mild cognitive impairment via protein-protein interaction aware explainable graph propagational network
Park S, Kim D, Lee H et al. Comput Biol Med · DOI · PubMed - RRM2 Is a CTNNB1 Transport Regulator Promoting Colon Cancer Progression
Moon SU, Lee JH, Shah M et al. Anticancer Res · DOI · PubMed - Safe Utilization and Sharing of Genomic Data: Amendment to the Health and Medical Data Utilization Guidelines of South Korea
Park H, Park J, Woo HG et al. Cancer Res Treat · DOI · PubMed - Transcriptomic profiling of intermediate cell carcinoma of the liver
Jang B, Kwon SM, Kim JH et al. Hepatol Commun · DOI · PubMed
2023
- Assessment of neutralization susceptibility of Omicron subvariants XBB.1.5 and BQ.1.1 against broad-spectrum neutralizing antibodies through epitopes mapping
Shah M, Woo HG. Front Mol Biosci · DOI · PubMed - CCIDB: a manually curated cell-cell interaction database with cell context information
Noh JY, Lee HI, Choi JH et al. Database (Oxford) · DOI · PubMed - Cancer signature ensemble integrating cfDNA methylation, copy number, and fragmentation facilitates multi-cancer early detection
Kim SY, Jeong S, Lee W et al. Exp Mol Med · DOI · PubMed - Critical roles of parkin and PINK1 in coxsackievirus B3-induced viral myocarditis
Jin U, Park SJ, Lee BG et al. Microbes Infect · DOI · PubMed - Effect of Janus Kinase 3 Inhibitor on Sebaceous Gland Regeneration during Skin Wound Healing
Jo WT, Kim AY, Woo HG et al. Ann Dermatol · DOI · PubMed - Rational strategies for enhancing mAb binding to SARS-CoV-2 variants through CDR diversification and antibody-escape prediction
Shah M, Shin JY, Woo HG. Front Immunol · DOI · PubMed - Single-cell transcriptome profiling of the stepwise progression of head and neck cancer
Choi JH, Lee BS, Jang JY et al. Nat Commun · DOI · PubMed - THOC2 expression and its impact on 5-fluorouracil resistance in glioblastoma multiforme
Lee YJ, Jung JH, Chang DY et al. Am J Cancer Res · PubMed
2022
- CGV: Cancer Genome Viewer, a web service for integrative cancer genome and pharmacogenomic data analysis
Choi JH, Choi HS, Cho SH et al. Bioinformatics · DOI · PubMed - Consensus subtypes of hepatocellular carcinoma associated with clinical outcomes and genomic phenotypes
Lee SH, Yim SY, Jeong YS et al. Hepatology · DOI · PubMed - Molecular and radiopathologic spectrum between HCC and intrahepatic cholangiocarcinoma
Jeon Y, Kwon SM, Rhee H et al. Hepatology · DOI · PubMed - NAMPT mitigates colitis severity by supporting redox-sensitive activation of phagocytosis in inflammatory macrophages
Hong SM, Lee AY, Hwang SM et al. Redox Biol · DOI · PubMed - Omicron: A Heavily Mutated SARS-CoV-2 Variant Exhibits Stronger Binding to ACE2 and Potently Escapes Approved COVID-19 Therapeutic Antibodies
Shah M, Woo HG. Front Immunol · DOI · PubMed - The paradigm of immune escape by SARS-CoV-2 variants and strategies for repositioning subverted mAbs against escaped VOCs
Shah M, Woo HG. Mol Ther · DOI · PubMed
2021
- ⭐ Endoplasmic Reticulum Stress Induces CAP2 Expression Promoting Epithelial-Mesenchymal Transition in Liver Cancer Cells
Yoon S, Shin B, Woo HG. Mol Cells · DOI · PubMed - Global spliceosome activity regulates entry into cellular senescence
Kwon SM, Min S, Jeoun UW et al. FASEB J · DOI · PubMed - Lung and lymph node metastases from hepatocellular carcinoma: Comparison of pathological aspects
Woo HY, Rhee H, Yoo JE et al. Liver Int · DOI · PubMed - MRPS31 loss is a key driver of mitochondrial deregulation and hepatocellular carcinoma aggressiveness
Min S, Lee YK, Hong J et al. Cell Death Dis · DOI · PubMed - ⭐ Molecular Perspectives of SARS-CoV-2: Pathology, Immune Evasion, and Therapeutic Interventions
Shah M, Woo HG. Mol Cells · DOI · PubMed - PathogenicVariants Are Frequent Among the Korean General Population
Kang CH, Kim YM, Kim YJ et al. Neurol Genet · DOI · PubMed - Tumor suppressor RBM24 inhibits nuclear translocation of CTNNB1 and TP63 expression in liver cancer cells
Moon SU, Kim JH, Woo HG. Oncol Lett · DOI · PubMed - USO1 isoforms differentially promote liver cancer progression by dysregulating the ER-Golgi network
Yoon S, Choi JH, Shah M et al. Carcinogenesis · DOI · PubMed - YAP inactivation in estrogen receptor alpha-positive hepatocellular carcinoma with less aggressive behavior
Jeon Y, Yoo JE, Rhee H et al. Exp Mol Med · DOI · PubMed
2020
- BCL2 Interacting Protein 3-like/NIX-mediated Mitophagy Plays an Important Role in the Process of Age-related Hearing Loss
Kim YJ, Choo OS, Lee JS et al. Neuroscience · DOI · PubMed - MLH1 single-nucleotide variant in circulating tumor DNA predicts overall survival of patients with hepatocellular carcinoma
Kim SS, Eun JW, Choi JH et al. Sci Rep · DOI · PubMed - Mitoribosome Defect in Hepatocellular Carcinoma Promotes an Aggressive Phenotype with Suppressed Immune Reaction
Kwon SM, Lee YK, Min S et al. iScience · DOI · PubMed - Mutations in the SARS-CoV-2 spike RBD are responsible for stronger ACE2 binding and poor anti-SARS-CoV mAbs cross-neutralization
Shah M, Ahmad B, Choi S, Woo HG. Comput Struct Biotechnol J · DOI · PubMed - PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells
Kim JJ, Lee SY, Choi JH et al. Mol Cell · DOI · PubMed - Sex-Biased Molecular Signature for Overall Survival of Liver Cancer Patients
Kim SY, Song HK, Lee SK et al. Biomol Ther (Seoul) · DOI · PubMed - Transcriptional regulatory networks of tumor-associated macrophages that drive malignancy in mesenchymal glioblastoma
Sa JK, Chang N, Lee HW et al. Genome Biol · DOI · PubMed - scTyper: a comprehensive pipeline for the cell typing analysis of single-cell RNA-seq data
Choi JH, In Kim H, Woo HG. BMC Bioinformatics · DOI · PubMed
2019
- Dynamics of Genomic, Epigenomic, and Transcriptomic Aberrations during Stepwise Hepatocarcinogenesis
Jee BA, Choi JH, Rhee H et al. Cancer Res · DOI · PubMed - ⭐ EPHB6 mutation induces cell adhesion-mediated paclitaxel resistance via EPHA2 and CDH11 expression
Yoon S, Choi JH, Kim SJ et al. Exp Mol Med · DOI · PubMed - Embryonic Stem Cell-Derived mmu-miR-291a-3p Inhibits Cellular Senescence in Human Dermal Fibroblasts Through the TGF-β Receptor 2 Pathway
Bae YU, Son Y, Kim CH et al. J Gerontol A Biol Sci Med Sci · DOI · PubMed - Functional Genomic Complexity Defines Intratumor Heterogeneity and Tumor Aggressiveness in Liver Cancer
Kwon SM, Budhu A, Woo HG et al. Sci Rep · DOI · PubMed - RNAi Screening-based Identification of USP10 as a Novel Regulator of Paraptosis
Kim JY, Lee DM, Woo HG et al. Sci Rep · DOI · PubMed - SEQprocess: a modularized and customizable pipeline framework for NGS processing in R package
Joo T, Choi JH, Lee JH et al. BMC Bioinformatics · DOI · PubMed
2018
- Identification of genomic aberrations associated with lymph node metastasis in diffuse-type gastric cancer
Choi JH, Kim YB, Ahn JM et al. Exp Mol Med · DOI · PubMed - Identification of novel susceptibility loci associated with hepatitis B surface antigen seroclearance in chronic hepatitis B
Kim TH, Lee EJ, Choi JH et al. PLoS One · DOI · PubMed - Keratin 19 Expression in Hepatocellular Carcinoma Is Regulated by Fibroblast-Derived HGF via a MET-ERK1/2-AP1 and SP1 Axis
Rhee H, Kim HY, Choi JH et al. Cancer Res · DOI · PubMed - ⭐ Multiplatform Genomic Roadmap of Hepatocellular Carcinoma: A Matter of Molecular Heterogeneity
Woo HG, Kim YJ. Hepatology · DOI · PubMed - Recapitulation of pharmacogenomic data reveals that invalidation of SULF2 enhance sorafenib susceptibility in liver cancer
Yoon S, Lee EJ, Choi JH et al. Oncogene · DOI · PubMed
2017
- A Genome-Wide Association Study IdentifiesGene Polymorphism for Restless Legs Syndrome in a Korean Population
Cho CH, Choi JH, Kang SG et al. Psychiatry Investig · DOI · PubMed - ⭐ Integrative analysis of genomic and epigenomic regulation of the transcriptome in liver cancer
Woo HG, Choi JH, Yoon S et al. Nat Commun · DOI · PubMed - Mutations acquired by hepatocellular carcinoma recurrence give rise to an aggressive phenotype
Choi JH, Kim MJ, Park YK et al. Oncotarget · DOI · PubMed - Pan-cancer analysis of systematic batch effects on somatic sequence variations
Choi JH, Hong SE, Woo HG. BMC Bioinformatics · DOI · PubMed - The Ubiquitin-like with PHD and Ring Finger Domains 1 (UHRF1)/DNA Methyltransferase 1 (DNMT1) Axis Is a Primary Regulator of Cell Senescence
Jung HJ, Byun HO, Jee BA et al. J Biol Chem · DOI · PubMed - Transcriptomic and histopathological analysis of cholangiolocellular differentiation trait in intrahepatic cholangiocarcinoma
Rhee H, Ko JE, Chung T et al. Liver Int · DOI · PubMed
2016
- Underexpression of HOXA11 Is Associated with Treatment Resistance and Poor Prognosis in Glioblastoma
Se YB, Kim SH, Kim JY et al. Cancer Res Treat · DOI · PubMed
2015
- CDH13 and HCRTR2 May Be Associated with Hypersomnia Symptom of Bipolar Depression: A Genome-Wide Functional Enrichment Pathway Analysis
Cho CH, Lee HJ, Woo HG et al. Psychiatry Investig · DOI · PubMed - Identification of a mitochondrial defect gene signature reveals NUPR1 as a key regulator of liver cancer progression
Lee YK, Jee BA, Kwon SM et al. Hepatology · DOI · PubMed - Mitochondrial defect-responsive gene signature in liver-cancer progression
Lee YK, Woo HG, Yoon G. BMB Rep · DOI · PubMed - Recurrent Glioblastomas Reveal Molecular Subtypes Associated with Mechanistic Implications of Drug-Resistance
Kwon SM, Kang SH, Park CK et al. PLoS One · DOI · PubMed - Tumor suppressive effect of PARP1 and FOXO3A in gastric cancers and its clinical implications
Park SH, Jang KY, Kim MJ et al. Oncotarget · DOI · PubMed
2014
- A microchip filter device incorporating slit arrays and 3-D flow for detection of circulating tumor cells using CAV1-EpCAM conjugated microbeads
Kim YJ, Koo GB, Lee JY et al. Biomaterials · DOI · PubMed - Molecular classification of basal cell carcinoma of skin by gene expression profiling
Jee BA, Lim H, Kwon SM et al. Mol Carcinog · DOI · PubMed - Profiling of exome mutations associated with progression of HBV-related hepatocellular carcinoma
Woo HG, Kim SS, Cho H et al. PLoS One · DOI · PubMed - Role of cysteinyl leukotriene signaling in a mouse model of noise-induced cochlear injury
Park JS, Kang SJ, Seo MK et al. Proc Natl Acad Sci U S A · DOI · PubMed
2013
- Genomic copy number alterations with transcriptional deregulation at 6p identify an aggressive HCC phenotype
Kwon SM, Kim DS, Won NH et al. Carcinogenesis · DOI · PubMed - Implications of time-series gene expression profiles of replicative senescence
Kim YM, Byun HO, Jee BA et al. Aging Cell · DOI · PubMed - Patient-specific orthotopic glioblastoma xenograft models recapitulate the histopathology and biology of human glioblastomas in situ
Joo KM, Kim J, Jin J et al. Cell Rep · DOI · PubMed
2012
- A fibrous stromal component in hepatocellular carcinoma reveals a cholangiocarcinoma-like gene expression trait and epithelial-mesenchymal transition
Seok JY, Na DC, Woo HG et al. Hepatology · DOI · PubMed - A genome-wide association study of seasonal pattern mania identifies NF1A as a possible susceptibility gene for bipolar disorder
Lee HJ, Woo HG, Greenwood TA et al. J Affect Disord · DOI · PubMed - Perspectives of integrative cancer genomics in next generation sequencing era
Kwon SM, Cho H, Choi JH et al. Genomics Inform · DOI · PubMed - Transcriptomic profiling reveals hepatic stem-like gene signatures and interplay of miR-200c and epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma
Oishi N, Kumar MR, Roessler S et al. Hepatology · DOI · PubMed
2011
- Cross-species hybridization of microarrays for studying tumor transcriptome of brain metastasis
Park ES, Kim SJ, Kim SW et al. Proc Natl Acad Sci U S A · DOI · PubMed - Exploring genomic profiles of hepatocellular carcinoma
Woo HG, Park ES, Thorgeirsson SS, Kim YJ. Mol Carcinog · DOI · PubMed
2010
- ⭐ Association of TP53 mutations with stem cell-like gene expression and survival of patients with hepatocellular carcinoma
Woo HG, Wang XW, Budhu A et al. Gastroenterology · DOI · PubMed - Definition of ubiquitination modulator COP1 as a novel therapeutic target in human hepatocellular carcinoma
Lee YH, Andersen JB, Song HT et al. Cancer Res · DOI · PubMed - Differential regulation of proliferation and differentiation in neural precursor cells by the Jak pathway
Kim YH, Chung JI, Woo HG et al. Stem Cells · DOI · PubMed - ⭐ Identification of a cholangiocarcinoma-like gene expression trait in hepatocellular carcinoma
Woo HG, Lee JH, Yoon JH et al. Cancer Res · DOI · PubMed - Integrative analysis of proteomic signatures, mutations, and drug responsiveness in the NCI 60 cancer cell line set
Park ES, Rabinovsky R, Carey M et al. Mol Cancer Ther · DOI · PubMed
2009
- Central role of c-Myc during malignant conversion in human hepatocarcinogenesis
Kaposi-Novak P, Libbrecht L, Woo HG et al. Cancer Res · DOI · PubMed - ⭐ Identification of potential driver genes in human liver carcinoma by genomewide screening
Woo HG, Park ES, Lee JS et al. Cancer Res · DOI · PubMed
2008
- ⭐ Gene expression-based recurrence prediction of hepatitis B virus-related human hepatocellular carcinoma
Woo HG, Park ES, Cheon JH et al. Clin Cancer Res · DOI · PubMed
2007
- GAzer: gene set analyzer
Kim SB, Yang S, Kim SK et al. Bioinformatics · DOI · PubMed - GS2PATH: a web-based integrated analysis tool for finding functional relationships using gene ontology and biochemical pathway data
Yang JO, Charny P, Lee B et al. Bioinformation · DOI · PubMed - Gene expression profiling reveals different pathways related to Abl and other genes that cooperate with c-Myc in a model of plasma cell neoplasia
Park ES, Shaughnessy JD, Gupta S et al. BMC Genomics · DOI · PubMed - Heterologous tissue culture expression signature predicts human breast cancer prognosis
Park ES, Lee JS, Woo HG et al. PLoS One · DOI · PubMed
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